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Calcium sulphate bone regenertion material for alveolar and cystic leasion bone growth. self setting arious procedures have been advocated for regeneration of the periodontal apparatus, such as open flap debridement (OFD), natural or synthetic filling materials (bone grafts), and guided tissue regeneration (GTR).[¹] Bone grafts are any tissue or organ used for implantation or transplantation.[²] Historically, autogenous and allogenic bone have been used with some success. Several other bone replacement grafts have been developed for use in periodontal therapy to support bone formation and defect fill. Calcium sulfate acts as osteoconductive bone void filler that completely resorbs as the newly formed bone remodels and restores anatomic features and structural properties. Calcium sulfate acts as a resorbable osteoconductive scaffold that provides a structural framework for angiogenesis and osteogenesis while preventing soft tissue invasion by acting as a space filler. Two parallel series of mechanisms are triggered by the degradation of calcium sulfate into the deep bone defect. The first mechanism involves the release of calcium and sulfur ions in the biological environment, which results in carbonate apatite formation and calcium ion stimulation of cellular activity. The second mechanism is the precipitation of calcium phosphate, which leads to a transient local drop in pH. This causes surface demineralization of existing bone resulting in exposure of bioactive molecules and the release of growth factors such as transforming growth factors and bone morphogenetic proteins, which stimulates the growth of bone in defects filled with calcium sulfate ifu osspore CAS Bone void filler is injectable , mouldable and hard set product which can be drilled caclium hydroxyapatite:  40% calcium sulphate: 60% osteroconductive allow fast deposition of bone in 6-12 months. Osteoconductive, which means it forms a direct bond with osteoblasts that form new bone • Engineered to have a specific size, shape and crystallinity that confers high injectability and slow resorption rat can be injected though a 16G needle allowing injection into site non invasively God flow aloow full adaptation to cavity even in in accessible parts. The reaction is not exothermic Mixing accesories allow for wasy and simple method of mix and injection. The product is sterile.   code                 volume  xdental             1ml xmed1              5ml xmed 2             18ml plus accessories. Intended Use osspore BONE VOID FILLER is a fast settingresorbable ceramic bone graft substitute intended to fill gaps and voids .The material consists of a powder and a liquid component.   Osspore BONE VOID FILLER is indicated to be placed into bone voids or gaps in the bone i.e. extremities and pelvis (only during acetabular revision) not intrinsic to the stability of the bony structure.   The paste may be injected into the defect, molded by hand and ijected placed into the defect, or used to prepare beads that are placed into the defect. When fully set in vivo, BONE VOID FILLER is drillable and can be used to fix  prosthesis.   Contraindications

• Hypersensitivity to I any of the excipients
• Local infection at the site of implantation • Pregnancy
• Breastfeeding
• Manifest thyroxicosis

  Setting Properties: mixing time: 30 secs loading:         1min working time:  5 mintues. setting from 7 mins to 15 min to max hardness. Mixing: open sachet of powder into mixing pot. aspirate liquid from bottle and add to powder in pot. mix using spatula. Load syringe by pouring , insert piston and fix tip.   ready for use.